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Coronary Artery Disease

Adipose tissue adiponectin expression low in coronary artery disease

Published in Obesity and Diabetes Week, May 30th, 2005

Adiponectin expression in human epicardial adipose tissue in vivo is lower in patients with coronary artery disease.

"Intra-peritoneal adipose tissue is recognized as a predictor of metabolic syndrome and may contribute to the risk for cardiovascular disease by the production of adipocytokines, including adiponectin. Nevertheless, there is no knowledge on whether other visceral depots of adipose tissue, including the epicardial fat, have any metabolically active role, including production of adiponectin. Aim of the study: We sought to evaluate adiponectin protein expression in epicardial adipose tissue in vivo both in patients with severe coronary artery disease (CAD)...

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