Pancreatic Islets

Amyloid-positive islets distributed heterogeneously in type 2 diabetes

Published in Obesity and Diabetes Week, June 6th, 2005

Amyloid-positive islets are distributed heterogeneously in type 2 diabetic patients.

"Amyloid-containing (A+) islets are characteristic for type 2 diabetes (T2D), but their abundance seems variable among patients. It is unclear whether the distribution of A+ islets follows a certain pattern or occurs randomly throughout the pancreatic organ. We investigated the topography of A+ islets in eight pancreata of T2D patients and eight sex- and age-matched non-diabetic subjects," researchers in Belgium report.

"Transversal sections of head, body, and tail segments were stained with synaptophysin combined with Congo red to map/quantify islet tissue and...

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Source: Obesity and Diabetes Week (2005-06-06)

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