Atherosclerosis
Researchers reveal dual pathway for angiotensin II synthesis
Published in Obesity and Diabetes Week, June 13th, 2005
According to recent research from England, "The expression, localization, and function of enzymes responsible for the local formation of angiotensin II in atherosclerotic and nonatherosclerotic human coronary arteries were studied."
J.A.A. Borland and associates at the University of London reported, "Human epicardial coronary arteries expressed mRNA for both ACE and chymase. Immunobistochemical studies revealed that ACE was localized to the vascular endothelium, and to a lesser extent the medial smooth muscle cells, in both large...
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