Type 2 Diabetes Therapy

Metformin should be continued with insulin in diabetic patients

Published in Obesity and Diabetes Week, June 13th, 2005

Metformin therapy should be continued when starting insulin in patients with type 2 diabetes.

Researchers in England conducted a study "to test the effect of continuing metformin on weight gain and glycemic control in patients with poorly controlled type 2 diabetes who need to start insulin. Patients with type 2 diabetes on maximum tolerated oral agents referred for insulin conversion were recruited from hospital diabetes clinics into a double-blind randomized placebo-controlled trial. The 183 participants received metformin or placebo, titrated up to 2 g a day or maximum tolerated dose, with insulin started according to local practice. The main outcome measures were...

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Source: Obesity and Diabetes Week (2005-06-13)

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