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Diabetes

Angiopoietin-1 and angiopoietin-2 in diabetes mellitus, roles clarified

Published in Obesity and Diabetes Week, June 27th, 2005

Recently published research from England has clarified the roles of angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) in diabetes mellitus.

"Microvascular complications in diabetes identify those at risk of cardiovascular disease (CVD), suggesting a link between abnormal neovascularisation and CVD. This may be related to high plasma vascular endothelial growth factor (VEGF).

"We hypothesised increased Ang-1 and -2 in patients with diabetes that are related to VEGF, medium-term glycaemic control, endothelial damage/dysfunction and atherosclerosis," wrote H.S. Lim and colleagues, University of Birmingham.

"We measured plasma Ang-1...

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