Insulin Resistance
Adiponectin expression augments muscle insulin sensitivity in male rats
Published in Obesity and Diabetes Week, July 4th, 2005
According to recent research published in the journal Diabetes, "In this study, we investigated the chronic in vivo effect of adiponectin on insulin sensitivity and glucose metabolism by overexpressing the adiponectin protein in male Wistar rats using intravenous administration of an adenovirus (Adv-Adipo). Virally infected liver secreted adiponectin as high and low molecular weight complexes.
"After 7 days of physiological or supraphysiological hyper-adiponectinemia, the animals displayed enhanced insulin sensitivity during the glucose...
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