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Insulin Resistance

Researchers' findings advance insulin resistance research

Published in Obesity and Diabetes Week, July 4th, 2005

Investigators in The Netherlands, United States and Australia have published new insulin resistance data.

Study 1: Sixteen hours of fasting differentially affects hepatic and muscle insulin sensitivity in mice.

"Fasting readily induces hepatic steatosis. Hepatic steatosis is associated with hepatic insulin resistance. The purpose of the present study was to document the effects of 16 hours of fasting in wild-type mice on insulin sensitivity in liver and skeletal muscle in relation to tissue accumulation of triglycerides (TGs) and changes in mRNA expression of metabolically relevant genes. Sixteen hours of fasting did not show an effect on hepatic...

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