Published in Obesity and Diabetes Week, July 4th, 2005
According to a study from Spain, "Eicosapentaenoic acids, has been shown to stimulate leptin mRNA expression and secretion in 3T3-L1 cells. However, other studies have reported inhibitory effects of EPA on leptin expression and secretion in vivo and in vitro."
P. Perezmatute and colleagues, University Navarra, Pamploma explained, "To determine the direct effects of EPA on basal and insulin-stimulated leptin secretion, isolated rat adipocytes were incubated with EPA in the absence and presence of insulin. EPA (10, 100, and 200 M) increased basal leptin gene expression and...
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