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Diabetes

ISIS 113715 Improves Glucose Control in Patients With Type 2 Diabetes

Published in Obesity and Diabetes Week, July 11th, 2005

Isis Pharmaceuticals, Inc. announced ISIS 113715 reduced HbA1C and plasma glucose after 6 weeks of dosing.

The second-generation antisense drug did not cause any hypoglycemia (low blood sugar) and was well-tolerated. The data reported were from an interim analysis of a randomized, double-blind, placebo-controlled Phase 2 study in diabetic patients. Data were announced in an oral presentation by Lise Kjems, M.D., Ph.D., Executive Director, Metabolic Drug Development of Isis Pharmaceuticals, at the American Diabetes Association's (ADA) 65th Scientific Sessions in San Diego.

"The results we have reported for ISIS 113715 are encouraging. After just 6...

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