Diabetic Ketoacidosis

Both DKA and its treatment produce varying degrees of immunologic stress

Published in Obesity and Diabetes Week, August 15th, 2005

Both diabetic ketoacidosis (DKA) and its treatment produce varying degrees of immunologic stress.

"Recent studies support the presence of an inflammatory response during the treatment of diabetic ketoacidosis. The objectives of this study were to monitor the complement activation products C3a, C4a, Bb, and C5b-9 prior to, during, and after correction of DKA," researchers in the United States reported.

"All patients had increased levels of C3a at 6-8 h and 24 h (p<0.05). C4a was increased in only one patient. Bb showed an upward trend at 6-8 h, and was significantly elevated at 24 h (p<0.05); sC5b-9 was elevated in all patients prior to...

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Source: Obesity and Diabetes Week (2005-08-15)

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