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Weight Loss

Orlistat-induced weight loss reduces IL-6 and C-reactive protein levels

Published in Obesity and Diabetes Week, August 22nd, 2005

Orlistat-induced weight loss reduced interleukin-6 (IL-6) and C-reactive protein levels in obese subjects.

According to a study from Turkey, "Inflammation plays a major role in the pathogenesis of atherosclerosis. Obesity is an independent risk factor for cardiovascular disease, which may be mediated by increased secretion of proinflammatory cytokines by adipose tissue. The aim of this study is to investigate changes in the inflammatory markers IL-6 and high-sensitivity C-reactive protein (hs-CRP) during weight reduction with orlistat treatment in obese patients."

"Thirty-six obese (BMI: 36.1±3.4 kg/m2) and II non-obese (BMI:...

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