Published in Obesity and Diabetes Week, August 29th, 2005
"The animal model of streptozotocin-induced diabetes mellitus is used to study the changes produced by an increase in glycemia. The morphology of the pyramidal neurons of the prefrontal cortex, occipital cortex, and hippocampus was investigated in rats. The level of glucose in the blood was evaluated at 2 months, and the animals that exhibited more than 200 mg/dL were used. After 2 months of increasing blood-glucose level, the animals were sacrificed by an overdose of sodium pentobarbital and perfused intracardially with a 0.9% saline solution," scientists in Mexico report.
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