Published in Obesity and Diabetes Week, August 29th, 2005
Study 1: High plasma levels of leptin aren't associated with higher bone mineral density in insulin-resistant, premenopausal, obese women, reports a study from Lebanon.
"Obesity's protective effect on bone density may be mediated through increased muscle mass, fat mass, increased estrogen, and possibly insulin and leptin levels. To determine the impact of leptin and insulin on bone metabolism, we studied 48 obese, normally cycling, premenopausal women (age, 31±10 years; body mass index, 35.7±5 kg/m2): 28 insulin-resistant (IR) and 20...
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