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Angiotensin Converting Enzyme

Study investigated ACE I/D polymorphism in pediatric cancer patients

Published in Obesity and Diabetes Week, August 29th, 2005

A polymorphism of angiotensin converting enzyme is associated with severe circulatory compromise in febrile neutropenic children with cancer.

According to recent research from Hungary, "Angiotensin converting enzyme (ACE) gene insertion(I)/deletion(D) polymorphism influences the outcome of a number of cardiovascular diseases. ACE I/D polymorphism was investigated by PCR in 207 pediatric cancer patients and 144 controls."

E. Bardi and colleagues of the Debrecen University of Medicine reported, "ACE I/D distribution of patients and controls was similar. The frequency of the D allele and the prevalence of the deletion (DD) genotype were significantly...

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