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Diabetes Complications

Changes reported in ovarian steroidogenesis after thyroidectomy

Published in Obesity and Diabetes Week, September 19th, 2005

Changes occur in ovarian steroidogenesis in insulin-resistant, type 2 diabetic rats after thyroidectomy and gonadotropin treatment.

According to recent research from Japan, "The present study used thyroidectomized insulin-resistant, type 2 diabetic Goto-Kakizaki (GK) rats to assess whether insulin resistance and hypothyroidism modulate ovarian physiology. Animals were treated with daily injections of 5 IU equine chorionic gonadotropin for 5 days starting 1 week after thyroidectomy. Control groups included rats of GK and control (Wistar) strains treated only with equine chorionic gonadotropin or thyroidectomy, or with no treatment (intact)."

"In...

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