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Obesity & Diabetes

Weight gain suppression preserves insulin response to glucose

Published in Obesity and Diabetes Week, September 26th, 2005

Suppression of body weight gain preserves acute insulin response to glucose in the portal vein of spontaneously type 2 diabetic rats with visceral obesity.

According to recent research from Japan, "The age-related changes in acute insulin response after glucose loading and the influence of suppression of body weight gain were investigated using blood samples from portal and peripheral veins. We placed indwelling catheters in the portal vein of 12- and 24-week-old Otsuka Long-Evans Tokushima fatty (OLETF) rats (n=8, 12), and age-matched control Long-Evans Tokushima Otsuka (LETO) rats (n=8, 6)."

"To suppress the body weight gain, 6 out of 12 OLETF rats...

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