Insulin Delivery

State of insulin self-association does not affect pulmonary absorption

Published in Obesity and Diabetes Week, September 26th, 2005

State of insulin self-association does not affect its absorption from the pulmonary route.

According to a study from the United States, "This study is designed to compare and contrast the pulmonary absorption profiles of monomeric and hexameric insulin in the presence or absence of ethylene diamine tetraacetic acid (EDTA) or n-tetradecyl-beta-d-maltoside (TDM). The pulmonary absorption of two forms of insulin was studied by monitoring the changes in plasma insulin and glucose levels after intratracheal administration of monomeric or hexameric insulin into anesthetized rodents."

"EDTA or TDM was added to the formulation in order to evaluate if either...

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Source: Obesity and Diabetes Week (2005-09-26)

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