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Diabetes Treatment

Sitagliptin may offer best hope for type 2 diabetes patients

Published in Obesity and Diabetes Week, October 3rd, 2005

Results from two Phase II studies announced on September 14 support efficacy profile of sitagliptin, a novel DPP-IV inhibitor.

There are currently more than 194 million people with diabetes worldwide and this figure could exceed 333 million by 2025 if untreated. Current treatments for type 2 diabetes are often limited by their side effect profile, route of administration or difficulties in sustaining glucose control. As a result, there is a need for better tolerated treatments that do not cause weight gain and produce less risk of hypoglycemia for patients with type 2 diabetes.

The results of the two Phase II studies indicate that sitagliptin, an...

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