Published in Obesity and Diabetes Week, October 3rd, 2005
The patent covers a method for the synthesis of aminosterol compounds, such as EVIZON (squalamine lactate), squalamine for cancer, and trodusquemine (MSI-1436). These compounds have been identified as antiangiogenic agents, antibiotics, and sodium hydrogen antiporter (NHE) inhibitors.
Patent expiry occurs in April 2021.
Genaera's discovery of aminosterols including squalamine and trodusquemine has been...
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