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Cytology

Endothelial microparticles influence angiogenic dysfunction

Published in Obesity and Diabetes Week, October 10th, 2005

Endothelial microparticles influence angiogenic dysfunction.

"Endothelium derived microparticles have recently been described as a new marker of endothelial cell dysfunction. Increased levels of circulating microparticles have been documented in inflammatory disorders, diabetes mellitus, and many cardiovascular diseases," scientists in the United States report.

"Perturbations of angiogenesis play an important role in the pathogenesis of these disorders. We demonstrated previously that isolated endothelial microparticles (EMPs) impair endothelial function in vitro, diminishing acetylcholine-induced vasorelaxation and nitric oxide production by rat...

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