Obesity Pathogenesis

High-fat diet does not affect adipose tissue corticosterone levels

Published in Obesity and Diabetes Week, October 10th, 2005

A high-fat diet did not affect levels of corticosterone and 11-dehydrocorticosterone in KKA^Y and ob/ob mouse liver and adipose tissue.

According to recent research from Sweden, "The present study was performed to compare glucocorticoid levels in obese KKA^y and ob/ob mice with those in normal C5713L/6J mice, and the effect of high-fat diet on glucocorticoids in KKA^y and ob/ob mice. Liver, mesenteric and epididymal adipose tissue corticosterone and 11-dehydrocorticosterone concentrations as well as circulating corticosterone concentrations were measured. The KKA^y and ob/ob mice displayed elevated serum corticosterone levels...

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Source: Obesity and Diabetes Week (2005-10-10)

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