Diabetes Therapy
Treatment with metformin and insulin does not affect adiponectin levels
Published in Obesity and Diabetes Week, October 31st, 2005
According to recent research from Japan, "Decreased circulating levels of adiponectin, a novel adipose-derived adipocytokine, in obesity possibly contribute to the development of insulin resistance which is a major factor in the pathogenesis of type 2 diabetes. The present study was conducted to examine whether circulating and adipose tissue adiponectin levels are modulated by chronic treatment with metformin and intensive treatment with insulin in murine models of obesity and type 2 diabetes, db/db mice with a C57BL/KsJ genetic background."
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