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Diabetes Pathogenesis

White adipose tissue blood perfusion markedly increased in type 2 diabetic GK rat

Published in Obesity and Diabetes Week, October 31st, 2005

White adipose tissue blood perfusion is markedly increased in the type 2 diabetic GK rat.

According to a study from Sweden, "The aim of the present study was to evaluate and correlate islet to brown and white adipose tissue (WAT) blood perfusion in one obese rat and one nonobese rat with type 2 diabetes (obese Zucker [OZ] and GK rats, respectively). We measured blood perfusion with a microsphere technique in anesthetized animals and subsequently estimated the blood flow to seven different WAT depots and brown adipose tissue, in addition to the whole pancreas and pancreatic islets."

"Both GK and OZ rats had higher islet blood perfusion than their...

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