Obesity & Diabetes
Tesaglitazar ameliorates glucose and lipid intolerance in obese rats
Published in Obesity and Diabetes Week, November 21st, 2005
"Insulin impaired glucose tolerance, high circulating levels of free acids (FFA), and postprandial hyperlipidemia are associated with metabolic syndrome, which has been linked to increased risk of disease. We studied the metabolic responses to an oral triglyceride (TG) (1.7/2.0 g/kg lean body mass) load in three of conscious seven-hour fasted Zucker rats: lean healthy controls, insulin-resistant/dyslipidemic controls, and obese rats treated the dual peroxisome proliferator-activated receptor alpha/gamma agonist, 3 micromol/kg/day for four weeks," scientists...
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