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Obesity and Diabetes Week

Susan Hasty, Publisher

Table of Contents . . . November 28th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Obesity and Diabetes Week | Other Publications

Atherothrombosis Risk Factors - High rates of obesity and diabetes found in atherothrombosis patients

Disease Associations - SHIP2 is therapeutic target for treatment of both obesity and type 2 diabetes

Fitness & Wellness - Exercise decreases visceral and subcutaneous abdominal fat, inactivity raises fat levels

Pediatric Obesity - Endothelial inflammation in children linked to insulin resistance, lipid levels and BMI

Weight Loss - An obese, insulin-resistant, and/or IGT state promotes IL-6 release after high-fat meals

Alcohol Use - Higher serum DHEAS levels are found in type 2 diabetes patients who are drinkers

Antibacterial Agents - Initial antibiotic regimen has no influence on patient survival with bloodstream infection

Antioxidants - Benefit of Crataegus aronia linked to three distinct processes

Awards - Health benefits company receives award for weight management initiative

Bacteriology - Pathogenesis of S. aureus infection was investigated in diabetic mouse model

Business & Finance - Diabetes management company receives $1.5 M from sale of BiliChek assets

Diabetes Pathogenesis - Research add new data to diabetes pathogenesis body of knowledge

Cardiovascular Disease - Indian immigrants to the U.K. most susceptible to heart attacks, strokes

Clinical Trials - Developer of continuous glucose monitoring systems reports net loss of $6.3 million

Diabetes Complications - Diabetes and elevated blood pressure may combine to strengthen diabetic angiopathy

Diabetes Complications - Diabetes upregulates Bax expression and hastens retinal neuronal cell death in rat model

Diabetes Complications - Endostatin peptide may control diabetic nephropathy progression

Diabetes Complications - Higher glucose levels in diabetics is linked to higher risk of sudden cardiac death

Diabetes Pathogenesis - Researchers' data advance diabetes pathogenesis research

Diabetes Complications - Incidence of ESRD in patients with type 1 diabetes is lower than predicted

Diabetes Complications - Research helps identify precursors to foot disease in diabetes patients

Diabetes Complications - Rising diabetes rates prompt renewed emphasis on prevention of related heart disease, stroke

Diabetes Control - Effective patient education improves diabetes control in insulin treated patients

Diabetes Epidemiology - Altered KATP signaling is a major factor in glucokinase-deficient diabetes

Diabetes Epidemiology - CAPN10 mRNA expression is upregulated in NGT subjects after prolonged fat exposure

Diabetes Therapy - Researchers report details of new studies and findings in the area of diabetes therapy

Diabetes Genomics and Genetics - Findings advance knowledge in diabetes genomics and genetics research

Diabetes Management - Achilles tendon surgery helps prevent diabetic foot ulcers

Diabetes Pathogenesis - Antagonism of serotonin 5-HT2 receptor results in increased insulin sensitivity

Diabetes Pathogenesis - New findings in the area of diabetes pathogenesis detailed

Diabetes Therapy - Studies advance knowledge in diabetes therapy research

Diabetes Pathology - Elevated levels of MBL are found upon manifestation of type 1 diabetes in juveniles

Diabetes Pathology - Unexpected function for a key regulator of blood glucose levels is reported

Diabetes Research - U.S. FDA extends review period for Exubera by 3 months

Diabetes Risk Factors - Elevated levels of IL-18 are linked to high risk of developing type 2 diabetes

Diabetes Risk Factors - Factors linked to microalbuminuria remission in patients with diabetes are investigated

Diabetes Risk Factors - Mothers experience increased risk of diabetes-related hospitalization after loss of child

Diabetic Neuropathy - Researchers' data advance diabetic neuropathy research

Diabetes Risk Factors - Prototype software under development to assess diabetes risk with increased accuracy

Diabetes Therapy -  Tournefortia hartwegiana extracts demonstrate antidiabetic effect in rat model

Diabetes Therapy -  Zizyphus spina-christi leaves appear to be a safe alternative for lowering blood glucose

Diabetes Therapy - Advances in stenting improve the long-term outcome of diabetic patients

Diabetes Therapy - ApoB100 metabolism is not affected by exchange of s.c. insulin infusion with i.p. insulin infusion

Diabetes Therapy - Biopharma company to commence phase II oral insulin clinical trial

Metabolic Syndrome - Findings advance knowledge in metabolic syndrome research

Diabetes Therapy - Doxazosin may lower blood pressure by inhibiting sympathetic nervous activity in diabetics

Diabetes Therapy - Endocrinologist-supported advice for providers improves diabetes therapy

Diabetes Therapy - GLUT2 is potential therapeutic target for intestinal sugar delivery control

Diabetes Therapy - Metformin treatment improves outcome for patients with diabetes and heart failure

Diabetes Therapy - Patients treated by the 70/30 insulin algorithm achieved better glycemic control

Diabetes Therapy - Researchers provide details of new studies and findings in the area of diabetes therapy

Metabolic Syndrome - Reports advance knowledge in metabolic syndrome research

Diabetes-Associated Memory Loss - High frequency of early hypoglycemia episodes reduces spatial and long-term memory skills

Diabetic Nephropathy - Diabetes causes G6PD inhibition via PKA activation, adding to oxidative stress in kidney

Diabetic Neuropathy - Reports describe recent advances in diabetic neuropathy research

Metabolic Syndrome - Researchers' findings advance metabolic syndrome research

Diagnostics - CG-EGA effectively compared the accuracy of CGS systems in varying blood glucose ranges

Diagnostics - Capillary blood beta-hydroxybutyrate detection effective for diabetic ketosis treatment

Diagnostics - Laser scanning objectively assesses HIV-related facial lipoatrophy

Diagnostics - Standardized infrared thermography method developed for assessing foot temperature

Diet & Nutrition - Big portions as well as taste influence overeating, Cornell study finds

Diet & Nutrition - Diet high in saturated fat does not affect insulin sensitivity in rats offspring

Diet & Nutrition - Effects of vitamins/mineral regimen on diabetic glomerular and tubular dysfunction studied

Diet & Nutrition - Fried foods consumption outside home linked to poor diet and increased BMI in children

Diet & Nutrition - High-fat meal impairs vascular compliance in normal weight, insulin-resistant young subjects

Diet & Nutrition - Knowledge of diabetes and nutrition increases healthy beliefs and behaviors in communities

Diet & Nutrition - Research shows 9 out of 10 want healthier food, but don't want to pay for it

Diet & Nutrition - Survey shows severe obesity has great impact on career and social life

Disease Associations - Diabetes is linked to poor outcome in cardiac arrest patients admitted to hospital

Disease Associations - Stenting effective treatment of nonacute occluded coronary arteries in diabetics

Drug Delivery - Controlled release systems for insulin dose are crucial for patient comfort and compliance

Drug Delivery - Insulin plays important role in fractures healing, leading to increased diabetic recovery

Drug Development - Actoplus met is launched in the U.S. for type 2 diabetes

Drug Development - Muraglitazar developer to address cardiovascular safety profile questions

Endocrinology - Diabetes mellitus in men is associated with subnormal free testosterone levels

Endocrinology - Vitamin D system and genetic links to diabetes, obesity and vascular disease are reviewed

Environmental Health - Rats exposed to chlorpyrifos show risk factors for hyperlipidemia and hyperinsulinemia

Estrogen Treatment - Estrogen treatment prevents insulin resistance and hypertension in ovariectomized rats

Finance - Biopharmaceutical company reports third quarter revenues up 7%

Finance - Healthcare products provider announces revenues up 26.4%

Finance - Obesity management company regains compliance with Nasdaq minimum bid rule

Finance - Pharmaceutical company announces net loss of $20.0 million

Fitness & Wellness - Online diet company reports preliminary profit results for third quarter

Gastroenterology - BPD reverses all major components of metabolic syndrome in most patients

Gene Research - International consortium completes catalog of human genetic variation

Genetics & Genomics - Ability to compensate for insulin resistance linked to genetics of beta-cell growth

Genetics & Genomics - Acyl-CoA binding protein transcripts are expressed in adipose tissue

Genetics & Genomics - Ala98Val polymorphism of HNF1 alpha gene is linked to young ages at type 2 diabetes onset

Genetics & Genomics - Early-onset extreme obesity may be associated with MCHR1 polymorphisms

Genetics & Genomics - Insulin sensitivity after CR is not linked to mRNA expression of insulin signaling genes

Genetics & Genomics - Link found between lipid-related traits and lipid abnormalities in type 2 diabetes

Genetics & Genomics - MCP1 influences adipocyte function and may be linked to insulin resistance in tissues

Genetics & Genomics - Obstructive sleep apnea and obesity share many genetic risk factors

Genetics & Genomics - Polymorphisms in USF1 gene are not associated with type 2 diabetes in French Caucasians

Genetics & Genomics - TXNIP modulates overall gene transcription and may impair insulin secretion

Geriatrics - Diabetes mellitus is linked to increased fall risk in elderly at long-term care facilities

Hypertension - Recent findings illuminate research in hypertension

Inflammatory Disorders - Chronic inflammatory disorders are associated with enhanced levels of IL-6

Insulin - Immediate but not long-term intranasal insulin doses raise blood pressure

Insulin Delivery - Inhaled insulin has similar bioavailability, biopotency as subcutaneous insulin

Insulin Delivery - Oral insulin delivery successful using enteric-coated dry emulsion formulation

Kidney Disease - Older diabetes patients should be tested for concealed renal failure to prevent ADRs

Lipid Research - ER stress and SREBP-1 activation are involved in beta-cell glucolipotoxicity

Lipid Studies - Findings describe new data in lipid studies research

Medical Devices - Urgent medical device correction issued for blood glucose meters

Mental Health - Psychobiological profile improves after 5 kg of weight loss but declines after 10 kg

Metabolic Syndrome - Data advance knowledge in metabolic syndrome research

Obesity - Researchers propose role of CIDEA alleles on human obesity

Obesity Pathogenesis - Lower BNP levels observed in obese patients are not caused by enhanced NPR-C activity

Obesity Pathogenesis - Researchers' findings advance obesity pathogenesis research

Obesity and Diabetes - New findings in obesity and diabetes described

Oncology - Peripheral TNF-alpha levels are minor factor in nonobese type 2 diabetic insulin resistance

Oncology - Risk of lymphohematopoietic malignancies is relatively unrelated to body size

Pancreatic Cancer - U.S. FDA approves Tarceva in combination with gemcitabine chemotherapy for pancreatic cancer

Pediatric Diabetes - According to government agencies, 2 million U.S. youths have prediabetes

Pediatric Diabetes - Reduced beta-cell function in overweight youth with IFG may indicate type 2 diabetes risk

Pediatric Obesity - Lack of nutritional knowledge is associated with unhealthy eating habits and obesity

Personnel - Diabetes care company appoints Christopher Porter director of government affairs

Pharmaceutical Research - PPAR-alpha and -gamma agonists regulate adipocytokine expression and may avert type 2 diabetes

Polycystic Ovary Syndrome - Polycystic ovary syndrome features not seen in HIV-positive women with truncal adiposity

Prenatal Care - Fish oil supplements in pregnancy may reduce offspring's immune-mediated diseases

Preventive Medicine - U.S. HHS gives weight management program Innovation in Prevention award

Prostate Cancer - Obesity, weight gain are indicators of biochemical failure after prostatectomy

Proteomics - Angiotensin II and high glucose upregulate PCs expressed phagocyte-type NAD(P)H oxidase

Proteomics - UCP2 promoter polymorphism -866G/A linked to multiple sclerosis susceptibility

Quality Assurance - Michigan bariatric program earns surgery center of excellence designation

Statins - Appropriate lipid management regime for type 2 diabetics depends on CV health

Stem Cell Research - Stem cell therapy is proposed as future option for diabetes and heart failure

Type 2 Diabetes - Poorly controlled diabetic subjects may benefit from increased dietary vitamin C

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