Diabetes Complications
Diabetes upregulates Bax expression and hastens retinal neuronal cell death in rat model
Published in Obesity and Diabetes Week, November 28th, 2005
"This study was performed to determine whether early diabetes accelerates retinal neuronal cell death and inhibits neurite regeneration," scientists in Masscahusetts report.
T. Oshitari and colleagues working with Boston University used a streptozotocin injection to create five, out of ten, diabetic rats. They explained, "After 3 weeks of diabetes, retinas were isolated and retinal explants were cultured in serum-free media. On day 6, the number of neurites was counted in retinal explants obtained from control and diabetic rat retinas.
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