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Diabetes Complications

Data demonstrate major risk stratification benefits of Lp-PLA2 in diabetic patients

Published in Obesity and Diabetes Week, December 12th, 2005

diaDexus announced findings from two studies demonstrating that high levels of the proinflammatory enzyme, lipoprotein-associated phospholipase A2 (Lp-PLA2), are associated with an increased risk in cardiovascular disease across multiple populations.

All results were presented at the American Heart Association scientific sessions. The first study, "Lipoprotein-Associated Phospholipase A2 may Differentially Predict the Presence of Angiographic Coronary Artery Disease and Coronary Death across Glycemic Categories," showed that in diabetic patients, Lp-PLA2 conferred a greater than 2-fold increase in risk of coronary artery disease (CAD) or death from CAD, independent of...

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