Diabetes Pathogenesis
Increased visceral fat raises circulating cytokines, leads to muscle insulin resistance
Published in Obesity and Diabetes Week, December 12th, 2005
According to a study from the United States, "Maturing Sprague-Dawley (S-D) rats develop obesity and skeletal muscle insulin resistance. To investigate the relationship between fat mass and insulin responses, we performed surgical removal of the epididymal and retroperitoneal depots of visceral adipose tissue (VF) or sham surgery (SHAM) in male rats aged 4 months."
S.E. Borst and colleagues at Malcolm Randall VA Medical Center in Gainesville determined, "At sacrifice, 30 days later, the mass of visceral fat was 48% lower...
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