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Obesity and Diabetes Week

Susan Hasty, Publisher

Table of Contents . . . January 23rd, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Obesity and Diabetes Week | Other Publications

Diabetes Epidemiology - Two major quantitative trait loci and others relate to factors of metabolic syndrome

Diet & Nutrition - Maternal preoccupation with weight was linked to restrained eating behavior in offspring

Obesity Complications - Investigation found no influence of BMI on early total hip arthroplasty outcome

Obesity Pathogenesis - Leptin potentiates ADP-induced [Ca2+]i increase via JAK2 and tyrosine kinases

Obesity Therapy - Increased adiponectin levels may be effective in reducing insulin resistance in obese

Adolescent Health - Researchers identify factors associated with excess weight in teens

Atherosclerosis - AMPK activation by alpha-Lipoic acid prevents endothelial dysfunction in obese rats

Atherosclerosis - Perivascular white adipose tissue may assist in obesity-related atherosclerosis development

Atherosclerosis - Studies advance knowledge in atherosclerosis research

Atherosclerosis - Study suggests hypoadiponectinemia is a risk factor in early atherosclerosis development

Awards - Center for Surgical Weight Loss & Wellness designated as Center of Excellence

Awards - Diabetes drug developer recognized for leadership and product innovation

Business & Finance - Biopharma regains full compliance with Nasdaq listing requirements

Cancer Therapy - PPAR gamma-dependent effects of CLA on human glioblastoma cell line are investigated

Cardiac Rehabilitation - Completion of cardiac rehabilitation results in significant benefits for women

Cardiology - CRP was not linked to intimal-medial thickness, but was to coronary artery calcium levels

Cardiology - Diabetes mellitus did not impact angiographic and clinical outcomes of DES implantations

Cardiology - Fenofibrate did not significantly reduce coronary event risk in type 2 diabetics

Cardiology - Reports describe recent advances in cardiology research

Cardiology - Review discusses cardiovascular safety of antiobesity drug sibutramine

Cardiology - Sibutramine Cardiovascular Outcome Trial study is introduced

Chronic Kidney Disease - Detection and evaluation of chronic kidney disease using KDOQI guidelines are reviewed

Chronic Multi-Symptom Illness - Mysterious condition still more prevalent among Persian Gulf vets

Collaborations - Online diet and fitness company announces collaboration with Mayo Clinic

Collaborations - Pharmaceutical companies discuss terminating collaborative deal for oral type 2 diabetes therapy

Diabetes - Inflammatory biomarkers may mediate association between obesity and diabetes

Diabetes - New form of diabetes described

Diabetes Complications - Diabetics experience more adverse cardiac events following CABG surgery

Diabetes Complications - Gremlin gene expression prompts the formation of diabetic retinopathy

Diabetes Complications - Microangiopathy may influence normocytic normochromic anemia

Diabetes Complications - Pvu II polymorphism in LPL gene alter lipid/lipoprotein levels in NID diabetics

Diabetes Complications - SERCA hyperactivity may control lower BP and raised aortic muscle relaxation in diabetic rats

Diabetes Complications - Topical tretinoin was safe effective therapy for foot ulcers in diabetics

Diabetes Control - New intravenous insulin method for patients in intermediate-care improved outcomes

Diabetes Diagnostics - Serum AGE-elastin derived peptides may be useful markers for monitoring complications

Diabetes Diagnostics - Serum Cys C and urinary enzymes may be screening markers for renal dysfunction in diabetics

Diabetes Epidemiology - Maternal diabetes can cause permanent changes in NO-related vascular response

Diabetes Management - Medical advisory board issues tips to avoid diabetes-related hospitalization

Diabetes Pathogenesis - Findings describe new data in Diabetes Pathogenesis research

Diabetes Pathogenesis - Hyperglycemia is involved in higher aggregated protein deposition in diabetic mice glomeruli

Diabetes Pathogenesis - Insulin signaling in bone marrow stroma PA6 cells differs from extramedullary adipocytes

Diabetes Pathogenesis - Na/H exchange plays a central role in vascular changes in diabetes

Diabetes Pathogenesis - PPAR gamma agonists do not directly enhance Na+ transport via the epithelial Na+ channel

Diabetes Pathogenesis - Radiation may regulate pancreatic duodenal homeobox-1 protein expression

Diabetes Pathogenesis - Researchers' findings advance Diabetes Pathogenesis research

Diabetes Pathogenesis - Studies describe new findings in Diabetes Pathogenesis research

Diabetes Pathogenesis - Study of thioacetamide-treated diabetic rats showed NF-kappaB regulated cyclin D1 signaling

Diabetes Research -  C. esculenta protects membrane bound ATPase structural integrity and functional status

Diabetes Research - Antihyperglycemic effect of p-MCA acid is caused by increased insulin secretion and glycolysis

Diabetes Research - Endogenous secretory RAGE is protective factor for metabolic syndrome and atherosclerosis

Diabetes Research - Methylamine but not mafenide mimics insulin-like activity and shows antidiabetic properties

Diabetes Therapy - Experts suggest to prescribe orlistat only in conjunction with lifestyle modifications

Diabetes Therapy - Facilitated telephone peer support among diabetics may improve patient health

Diabetes Therapy - New data illuminates research in Diabetes Therapy

Diabetes Therapy - One year course of oral sulodexide delays the progression of diabetic nephropathy

Diabetes Therapy - Pioglitazone reduced oxidative stress in diabetic rats but not blood pressure

Diabetes Therapy - Recent studies add new data to Diabetes Therapy research

Diabetes Therapy - Research in Diabetes Therapy provides new insights

Diabetes Therapy - Researchers report details of new studies and findings in the area of Diabetes Therapy

Diabetes Therapy - Review examines pramlintide for treatment of type 1 and type 2 diabetes

Diabetes Therapy - Simvastatin may maintain antioxidant activity and structural organization in diabetic lung

Diabetes Therapy Complications - Review assesses prevalence of complications related to metformin use in diabetes treatment

Diagnostics - Combination of UKPDS or DCRS with ExE may optimize coronary artery disease detection

Diagnostics - LNA probes in genetic analysis provide simple assay for identifying diabetes-related alleles

Diagnostics - Leukocyte esterase and microscopic bacteriuria measures offer early UTI detection method

Diagnostics - NIH obesity treatment algorithm identified men at increased risk of premature mortality

Diagnostics - Researchers' work adds to diagnostics body of knowledge

Diet & Nutrition - Diet, but probably not obesity levels, affects hypothalamic energy balance signals

Diet & Nutrition - Education an important part of weight management for low-income mothers

Diet & Nutrition - Egg Nutrition Center-cofunded study indicates eggs for breakfast aid weight control

Diet & Nutrition - Lifestyle changes in at risk diabetes relatives improved blood lipids and insulin levels

Diet & Nutrition - Low carbohydrate diet did not appear to increase metabolic rate or thermogenesis

Diet & Nutrition - Low- and high-carbohydrate diets resulted in different body compositions in rat model

Diet & Nutrition - Low-carbohydrate diet is not more cost-effective than standard diet for weight loss

Diet & Nutrition - Orlistat improved weight loss and Eating Disorder Inventory score in obese

Diet & Nutrition - Review assessed angiopoietin-like proteins involvement in regulation of lipid metabolism

Diet & Nutrition - Study finds a high-dairy calcium diet did not significantly improve weight loss

Diet & Nutrition - Study finds role of TG-rich lipoproteins in adipose obese mRNA downregulation

Diet & Nutrition - apoE gene promoter polymorphism determines insulin sensitivity in response to dietary fat

Disease Associations - Increased risk of Alzheimer disease in type 2 diabetes patients is investigated

Disease Management - "Electronic nurse" helps homebound patients stay out of hospital

Drug Delivery - Guidelines for the use of continuous subcutaneous insulin infusion therapy are developed

Drug Development - Chinese Food and Drug Administration grants approval to market treatment for diabetes

Endocrinology - Cytoglobin induction may protect islet cells following transplantation

Endocrinology - Phosphoinositide signaling controls beta-cell secretion in insulin exocytosis

Endocrinology - Recombinant growth factor replacement therapy released in U.S.

Endocrinology - TORC2 modulates glucose output/insulin signaling by IRS2 expression and gluconeogenic genes

Finance - Biotech company announces $3.4 million in stock proceeds

Finance - Online weight management company redeems remaining minority interest for $304.8 million

Fitness & Wellness - Consumer health organization introduces nutritious vending snack options for employees

Fitness & Wellness - Exercise and green tea extract stimulated fat oxidation and prevented obesity

Fitness & Wellness - Most diabetic children meet pediatric guidelines for physical activity

Fitness & Wellness - Study finds exercise training results in a reduction in insulin resistance

Genetics & Genomics - Gly972Arg was a common mutation in the Irs-1 gene in Turkish with diabetes mellitus

Genetics & Genomics - Y chromosome and chromosome 2 genes influence metabolic and cardiovascular phenotypes

Health Promotion - Oklahoma aims to improve care for Native Americans with diabetes

Heart Disease - U.S. FDA allows barley products to claim reduction in risk of coronary heart disease

Hypertension - Nt-proBNP is inversely related to metabolic CV risk factors and the metabolic syndrome

Hypertension - Research add new data to hypertension body of knowledge

Medical Devices - Strength and endurance training lead to different glucose profiles in diabetics using CGMS

Mergers & Acquisitions - Definitive agreement signed for acquisition of insulin delivery company Animas Corporation

Metabolic Syndrome - Warning signs multiply risk of heart attack, stroke

Neurology - Physiological and pathological changes in glucose regulate brain Akt-GSK3

Obesity - Weight management company joins healthcare providers, others in weight loss programs

Obesity Complications - Obesity increases risk of new-onset atrial fibrillation after cardiac surgery

Obesity Complications - Obesity predicts increased overall complications following pancreas transplantation

Obesity Complications - One year post-transplant weight gain is a risk factor for graft loss

Obesity Complications - Review assesses benefits and risks of weight loss to overall health and mortality

Obesity Complications - Surgically induced weight loss reverses osteoarthritis in the knee joint

Obesity Control - Improved insulin resistance helps to prevent hypertension and dyslipidemia in obese youth

Obesity Epidemiology - An increased number of repeats in ESRRA23 of the ERR alpha gene is linked to a higher BMI

Obesity Epidemiology - MAGEL2 mutations do not commonly cause severe childhood-onset obesity

Obesity Pathogenesis - Adiponectin may be a protective factor in nonalcoholic fatty liver disease rates in obese

Obesity Pathogenesis - Hyperlipidemia and low carotenoid levels in obese youth may increase atherosclerosis risk

Obesity Pathogenesis - PVN galanin promotes obesity by causing muscle to use carbohydrates more than fat

Obesity Therapy - Acute preoperative weight loss improved surgical and postsurgical outcomes of LRYGBP

Obesity Therapy - After LAGB, weight loss was linked to lower circulating leptin, insulin and proinsulin levels

Obesity Therapy - Findings describe new data in Obesity Therapy research

Obesity Therapy - Group recommends adding more fruits, vegetables to daily intake

Obesity Therapy - LSG without 2nd-stage duodenal switch operation is most effective for weight loss

Obesity Therapy - Orexin antagonist reduced food intake in dietary-induced obesity and resistant rats

Obesity Therapy - Pediatric obesity-related counseling is increasing in the outpatient setting

Obesity Therapy - Polymorphisms in SLC6A2 and GRIN1 affect weight loss response of GW320659 in obese subjects

Obesity Therapy - Valsartan and atenolol effectively lowered blood pressure in obese hypertensives

Obesity Therapy - Weight loss 3 months after LAGB may be due to continued loss of visceral adipose tissue

Obesity Therapy - Weight loss, obesity predictions for 2006 announced

Obesity Therapy - Youth who feel increased parental acceptance after treatment maintain weight control

Pain Management - Pregabalin or morphine and gabapentin offer treatment options for neuropathic pain

Pancreas Research - Cell recovery and function are higher in islets cultured at 24 degrees C than those at 37 degrees C

Pediatrics - Parents' impressions of neighborhood safety linked to children's weight

Personnel - Arnold W. Donald named president, CEO of diabetes research funding foundation

Polycystic Ovary Syndrome - Abnormal blood glucose values are associated with polycystic ovary syndrome in Danish women

Product Development - Sugar substitute approved without restriction by European Union

Proteomics - Adiponectin represses gluconeogenesis independent of insulin in hepatocytes

Proteomics - Decreased RhoA expression may be involved in myocardium of diabetic rats

Proteomics - PIST modulates insulin secretion in MIN6 insulinoma cells by interacting with SSTR5

Proteomics - Transthyretin is functional component in pancreatic beta-cell stimulus-secretion coupling

Quality of Life - Patients report improved quality of life after simultaneous pancreas-kidney transplant

Stroke - Combination of hypertension and type 2 diabetes drastically increase stroke risk

Stroke - Comprehensive rehabilitation results in functional gains in posterior cerebral artery stroke

Sweat Production - Impairment in sweat production seen in diabetics may be due to heat sensitivity mechanism

Transplant Medicine - Intraepidermal nerve fiber depletion is found in skin biopsies of pancreas recipients

Transplant Medicine - Intraperitoneal neonatal porcine islet transplant proved safe in diabetic primate model

Transplant Medicine - Ischemic preconditioning improved transplantation survival from 25 to 88% in rat model

Transplant Medicine - Novel islet isolation facility finds donor characteristics had no influence on success

Transplant Medicine - Protocol developed for procurement of pancreas and kidneys from non-heart-beating donor

Transplant Medicine - Two-layer method showed advantages in pancreas preservation for successful islet isolation

Transplantation Biology - Laparoscopic gastric bypass is safe after orthotopic liver transplantation

Type 2 Diabetes - Hand grip strength is lowered in patients with type 2 diabetes mellitus

Type 2 Diabetes - Low BMI and microalbuminuria absence were independent indicators of long-term BP control

Type 2 Diabetes - Prevalence of type 2 diabetes is increasing among youth in the USA and Asia

Type 2 Diabetes - Targeting PPAR alpha and gamma activity may improve dyslipidemia risk in diabetics

Vascular Research - Study finds insulin has a vasodilatory activity on skin microvascular district

Weight Loss - Relation between degree of weight loss and risk factor reduction is discussed

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