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Pediatric Obesity Pathogenesis

Peptide YY regulates energy homeostasis in obese children before and after weight loss

Published in Obesity and Diabetes Week, January 30th, 2006

Peptide YY is a regulator of energy homeostasis in obese children before and after weight loss.

According to a study from Germany, "The gut hormone peptide YY3-36 (PYY) reduces food intake via hypothalamic Y2 receptors in the brain. There is not much known about PYY in obese children. The objective of this study was to investigate the role of PYY in the metabolic changes in obese children and its change during weight loss."

C.L. Roth and colleagues at the University of Bonn examined "73 obese children and 45 age-matched normal-weight children [at a university medical center]. [They] determined fasting serum total PYY and leptin by RIA in obese and...

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