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Type 2 Diabetes

HFE genetic variability and heme iron intake are associated with type 2 diabetes risk

Published in Obesity and Diabetes Week, January 30th, 2006

HFE genetic variability and heme iron intake are associated with type 2 diabetes risk in U.S. women.

In a recent study, researchers in the United States conducted a study "to determine whether the HFE gene variants H63D and C282Y are associated with body iron stores and the risk of type 2 diabetes[.] [We] conducted a nested case-control study of 714 incident cases of type 2 diabetes and 1,120 matching control subjects in a prospective cohort, the Nurses' Health Study."

L. Qi and colleagues, Harvard University, discovered, "In both healthy control and diabetic case subjects, H63D homozygosity, C282Y, and the compound heterozygotes were associated with...

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