Diabetes Complications
Diabetic rats experienced increased AGE, AGER and NFKB expression in lacrimal glands
Published in Obesity and Diabetes Week, January 30th, 2006
Investigators in Brazil recently conducted a study, "To assess the involvement of the advanced glycation end-products (AGE)-specific receptor (AGER, also known as RAGE) axis and nuclear factor kappa-B (NFKB, also known as NFkappaB) activation in the development of lacrimal gland and tear film dysfunction in diabetes, the present study evaluated: (1) lacrimal gland and tear film alterations in diabetic rats; and (2) the expression of AGE, AGER and NF-kB in ocular tissues of normoglycemic and diabetic rats."
M. Alves and...
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