Diabetes Research
Autoantibody response may mark the time to onset of type 1 diabetes
Published in Obesity and Diabetes Week, January 30th, 2006
"Islet cell autoantibodies are strongly associated with the development of type 1 diabetes. The appearance of autoantibodies to one or several of the autoantigens-GAD65, IA-2, or insulin-signals an autoimmune pathogenesis of beta-cell killing," scientists in the United States report in their discussion.
C. Pihoker and colleagues at the University of Washington explained, "A beta-cell attack may be best reflected by the emergence of autoantibodies dependent on the genotype risk factors, isotype, and subtype of the autoantibodies as well as their epitope specificity. It is speculated...
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