Diabetes Research
Individual mice can be distinguished by their islet calcium oscillation period
Published in Obesity and Diabetes Week, January 30th, 2006
According to recent research from the United States, "Pulsatile insulin secretion in vivo is believed to be derived, in part, from the intrinsic glucose-dependent intracellular calcium concentration ([Ca2+]i ) pulsatility of individual islets. In isolation, islets display fast, slow, or mixtures of fast and slow [Ca2+]i oscillations. We show that the period of islet [Ca2+]i oscillations is unique to each mouse, with the islets from an individual mouse demonstrating similar rhythms to one another."
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