Obesity Pathogenesis
Activation of cAMP or PPARgamma pathway increases oxidation in white adipocytes
Published in Obesity and Diabetes Week, January 30th, 2006
"Mitochondrial biogenesis is a complex process, and several factors and signaling pathways regulate this process in muscle or brown adipocytes. The aim of the study was to explore pathways affecting mitochondrial biogenesis and fatty acid oxidation (FAO) in human white adipocytes," researchers in the United States report.
I. Bogacka and colleagues working with the Pennington Biomedical Research Center in Baton Rouge explained, "Human preadipocytes obtained from liposuction samples were differentiated in vitro. On the 10th day of differentiation, 4 mcM forskolin...
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