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Anesthesia

Anesthesia can cause sustained hyperglycemia in C57/BL6J mice

Published in Obesity and Diabetes Week, February 13th, 2006

Anesthesia can cause sustained hyperglycemia in C57/BL6J mice and should be considered when treating diabetics.

According to recent research from the United States, "Effects of anesthesia on the blood glucose of C57/BL6J mice were evaluated under conditions commonly used for testing retinal sensitivity with electroretinographic (ERG) recordings."

E.T. Brown and colleagues working at the State University of New York Upstate Medical University evaluated "the effects of four anesthetics: nembutal (50 mg/kg), pentothal (100 mg/kg), avertin (240 mg/kg), and ketamine/xylazine (100 mg/kg) using saline as control. We measured blood glucose (BG) levels from...

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