Obesity Pathogenesis
Capsaicin-induced sensory desensitization improves glucose tolerance in obese Zucker rats
Published in Obesity and Diabetes Week, February 20th, 2006
According to recent research published in the European Journal of Endocrinology, "It has earlier been demonstrated that capsaicin-induced desensitization improves insulin sensitivity in normal rats. However, whether increased capsaicin-sensitive nerve activity precedes the onset of insulin resistance in diet-induced obesity - and, therefore, might be involved in the pathophysiology -is not known. Further, it is of relevance to investigate whether capsaicin desensitization improves glycemic control even in obese individuals and we therefore chose the obese Zucker rats...
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