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Complementary & Alternative Medicine
Green tea inhibition of resistin gene expression in adipocytes depends on ERK pathway
March 6th, 2006
Inhibitory effect of green tea (-)- epigallocatechin gallate on resistin gene expression in 3T3-L1 adipocytes depends on the ERK pathway. According to a study from Taiwan, "Resistin (Rstn) is known as an adipocyte-specific secretory hormone that can cause insulin resistance and decrease adipocyte differentiation. By contrast, green tea catechins, especially (-)-epigallocatechin gallate (EGCG), have been reported as body weight and diabetes chemopreventatives. Whether EGCG regulates production of Rstn is unknown." H.S. Liu and colleagues working with the National Central University conducted and investigation with 3T3-L1 adipocytes and discovered...
Source: Obesity & Diabetes Week (2006-03-06)
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