Obesity & Diabetes Week
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Diabetes Pathogenesis
FoxO1 protein involved in regulating beta cell numbers during insulin resistance
March 6th, 2006
Researchers have identified a protein that is involved in regulating beta cell numbers during insulin resistance. Diabetes is a disease caused by the inability of the body to produce or respond to insulin (insulin resistance), and the main cells that fail in this disease are insulin-producing cells of the pancreas called beta cells. Although beta cells are renewed during adult life, during insulin-resistant states the beta cells become hyperplastic (making too many cells) to compensate for their impaired function. Unfortunately, the mechanism for this hyperplasia is unclear. Now, in a study appearing online on February 16, 2006, in advance of print...
Source: Obesity & Diabetes Week (2006-03-06)
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