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Obesity & Diabetes Week

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Diabetes Pathogenesis



New findings in diabetes pathogenesis described



March 6th, 2006

Data on diabetes pathogenesis are outlined in reports from Scotland, France and the United States.

Study 1: 11beta-HSD-1 may be a therapeutic target for the idiopathic metabolic syndrome.

"Despite major advances in understanding monogenic causes of morbid obesity, the complex genetic and environmental etiology of idiopathic metabolic syndrome remains poorly understood. One hypothesis suggests that similarities between the metabolic disease of plasma glucocorticoid excess (Cushing syndrome) and idiopathic metabolic syndrome results from increased glucocorticoid reamplification within adipose tissue by 11 beta-hydroxysteroid dehydrogenase type 1...


Source: Obesity & Diabetes Week (2006-03-06)

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