Published in Obesity and Diabetes Week, March 6th, 2006
"The inability of insulin to stimulate glucose metabolism in skeletal muscle fibers is a classic characteristic of type 2 diabetes. Using the nonobese Goto-Kakizaki rat as an established animal model of this type of diabetes, sucrose gradient centrifugation studies were performed and confirmed the abnormal subcellular location of the glucose transporter GLUT4. In addition, this...
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