Obesity & Diabetes Week
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Diabetes Pathogenesis
New findings in the area of diabetes pathogenesis detailed
March 6th, 2006
Data on diabetes pathogenesis are outlined in reports from Ireland, the United States and the United Kingdom. Study 1: Expression of dystrophin-dystroglycan complex and syntrophin-nitric oxide synthase complex may control insulin resistance in diabetic skeletal muscles. "The inability of insulin to stimulate glucose metabolism in skeletal muscle fibers is a classic characteristic of type 2 diabetes. Using the nonobese Goto-Kakizaki rat as an established animal model of this type of diabetes, sucrose gradient centrifugation studies were performed and confirmed the abnormal subcellular location of the glucose transporter GLUT4. In addition, this...
Source: Obesity & Diabetes Week (2006-03-06)
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