Obesity & Diabetes Week
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Diabetes Pathogenesis
Role of natural killer T cells in autoimmune diabetes in nonobese diabetic mice is reviewed
March 6th, 2006
The role of CD1d-restricted natural killer T cells in the control of autoimmune diabetes in nonobese diabetic mice is reviewed. According to a recent review published in the journal Clinical and Experimental Immunology, "Manipulation of the immune response to specifically prevent autoaggression requires an understanding of the complex interactions that occur during the pathogenesis of autoimmunity. Much attention has been paid to conventional T lymphocytes recognizing peptide antigens presented by classical major histocompatibility complex (MHC) class I and II molecules, as key players in the destructive autoreactive process." S.L. Cardell at...
Source: Obesity & Diabetes Week (2006-03-06)
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