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Obesity & Diabetes Week

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Diabetes Pathogenesis



Team targets proteins that contribute to diabetes, obesity



March 6th, 2006

Researchers at the University of Massachusetts Medical School (UMMS) have found proteins that regulate insulin sensitivity and the ability of cells to burn fat.

The proteins were identified using a new testing process the UMMS team developed based on RNA-interference to selectively silence genes. The proteins were found to be integral to the mechanisms that allow cells to process insulin, absorb sugar, and promote the build up or the burning of fatty tissues.

"The findings in these papers give us a better understanding of the biological links between obesity and type 2 diabetes. And the proteins we've identified as new potential drug targets may have...


Source: Obesity & Diabetes Week (2006-03-06)

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