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Alcohol Use
AA-AGE cytotoxicity is important in alcoholic-induced neuronal degeneration
March 6th, 2006
Acetaldehyde-derived advanced glycation end-product cytotoxicity is important in alcoholic-induced neuronal degeneration. According to recent research published in the journal Alcoholism - Clinical and Experimental Research, "The Maillard reaction that leads to the formation of advanced glycation end-products (AGEs) plays an important role in the pathogenesis of angiopathy in diabetic patients, in aging, and in neurodegenerative processes." M. Takeuchi and colleagues at Hokuriku University proposed that "acetaldehyde (AA), one of the main metabolites of alcohol, may be involved in alcohol-induced neurotoxicity in vivo by formation of...
Source: Obesity & Diabetes Week (2006-03-06)
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