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Obesity and Diabetes Week

Susan Hasty, Publisher

Table of Contents . . . March 13th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Obesity and Diabetes Week | Other Publications

Endocrinology - Insulin stimulates L-carnitine accumulation in human skeletal muscle

Natural Products -  Salacia oblonga root improves cardiac lipid metabolism in Zucker diabetic fatty rats

Obesity Pathogenesis - Adipokine expression profile in adipocytes increases with obesity and hyperinsulinemia

Obesity Therapy - Morbid obesity therapy with SAGB is less expensive and more effective

Type 2 Diabetes - Statins use related to increased LPL activity and results in TRL particle delipidation

Aesthetic Medicine - Despite risks, adults not shying away from cosmetic surgery and other treatments

Amyotrophic Lateral Sclerosis - First patient completes arimoclomol phase II clinical trial

Anesthesia - Morbidly obese may experience improved intraoperative oxygenation postalveolar recruitment

Atherosclerosis - Atherosclerosis instigated by adipokine gene expression following oxidative stress

Atherosclerosis - Diabetics with delayed triglyceride metabolism appear to have higher atherosclerosis risk

Awards - St. Vincent Charity Hospital named center of excellence by bariatric surgery society

Bipolar Disorder - Bipolar disorder linked to lithium sensitive protein in mammals' internal clock

Cardiology - New findings in cardiology described

Cardiovascular Disease - Acarbose reduces cardiovascular event risk in patients with impaired glucose metabolism

Cardiovascular Disease - Angiotensin II antagonists offer therapeutic benefits to cardiovascular disease patients

Cardiovascular Disease - Obese middle-aged have higher risk of mortality from CHD and diabetes

Cardiovascular Disease - Renal transplant recipients with altered glycemia show higher BMI and Hb1Ac

Chronic Hepatitis C - Age and diabetes affect the severity of liver damage in chronic hepatitis C

Clinical Trials - Human clinical trials begun on whole food liquid nutritional diabetes product

Clinical Trials - Phase II clinical trial in neuropathic pain begins

Diabetes Complications - Adenosine receptor expression is altered in the hearts of diabetic rats

Diabetes Complications - Angiotensin-converting enzyme correlates with angiogenesis factors in diabetic retinopathy

Diabetes Complications - CAD screening guidelines in asymptomatic type 2 diabetes mellitus evaluated

Diabetes Complications - Cardiac function and ischemic tolerance sensitivity increase after metabolic control loss

Diabetes Complications - Diabetic neuropathy is mediated by altered Na+ channel function in DRG neurons and A-fibers

Diabetes Complications - Elevated HbA1c levels linked to improved survival in diabetes and advanced systolic HF

Diabetes Complications - Glucose-induced ROS initiate podocytes apoptosis at diabetic nephropathy onset

Diabetes Complications - Hepatocyte growth factor reflects fibroproliferation, but not angiogenesis, in diabetic retinopathy

Diabetes Complications - Impaired angiogenesis factors are not linked to vessel dysfunction in diabetic foot

Diabetes Complications - Insulin resistance and atherosclerosis risk increase with adiponectin levels

Diabetes Complications - Pioglitozone reduces leptin levels and improves endothelial function in type 2 diabetics

Diabetes Complications - Postprandial hyperglycemia may increase atherosclerotic cardiovascular disease risk

Diabetes Diagnostics - High IMTG in insulin-resistant and endurance-trained state may offer resistance marker

Diabetes Diagnostics - Lowering FPG diagnostic for diabetics to 7.0 mmol/L supported by data

Diabetes Epidemiology - -23HphI+/- is a common functional single nucleotide polymorphism at IDDM2

Diabetes Epidemiology - Breast-feeding reduces type 1 diabetes risk

Diabetes Epidemiology - Type 2 diabetes risk influenced by -112A>C polymorphism

Diabetes Pathogenesis - Adiponectin is linked to higher insulin sensitivity and lower abdominal fat

Diabetes Pathogenesis - Co-stimulatory signal blockage prolongs the survival of islet xenografts

Diabetes Pathogenesis - Diabetes mellitus risk increases in women exposed to arsenic

Diabetes Pathogenesis - Microalbuminuria regression was high in diabetics under glycemic and blood pressure control

Diabetes Pathogenesis - Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression

Diabetes Pathogenesis - Researchers' work adds to diabetes pathogenesis body of knowledge

Diabetes Pathogenesis - Studies add new findings to diabetes pathogenesis body of knowledge

Diabetes Therapy - Diabetes researchers show adult human pancreas stem cells can be transformed into insulin-producing cells

Diabetes Therapy - Diabetics experience less CV events after low-dose statin therapy with atorvastatin

Diabetes Therapy - Insulin analog reversed myocardial perfusion deviations by improving glucose control

Diabetes Therapy - Muraglitazar improves diabetes and preserve beta-cell function in db/db mice

Diabetes Therapy - Nitric oxide-glucose uptake mechanism may be type 2 diabetes therapeutic target

Diabetes Therapy - Proinsulin levels are elevated in type 2 diabetics treated with sulfonylurea

Diabetes Therapy - Rapid angiogenesis sustains islet transplant survival in diabetes models

Diabetes Therapy - Reports advance knowledge in diabetes therapy research

Diabetes Therapy - Researchers describe findings in diabetes therapy studies

Diabetes Therapy - Researchers report details of new studies and findings in the area of diabetes therapy

Diabetes/Epilepsy Associations - Type 1 diabetes and idiopathic generalized epilepsy link discovered

Diabetic Nephropathy - Researchers' work adds to diabetic nephropathy body of knowledge

Diabetic Neuropathy - Duloxetine HC1 therapy for diabetic nerve pain is safe and well-tolerated, study shows

Diagnostics - Researchers describe findings in diagnostics studies

Diet & Nutrition - Dairy foods may assist in the management of obesity and overweight

Diet & Nutrition - Diet book asserts that diets fail due to lack of serotonin

Diet & Nutrition - Hypocaloric low-fat diet increases PUFAn-3 in muscle membrane phospholipids of obese

Diet & Nutrition - San Diego's African American community focus of health and nutrition forum

Diet & Nutrition - Type 1 diabetes rates worldwide are linked to nutritional factors and meat consumption

Disease Control - Self-rated health factors for metabolic syndrome among middle-aged men underestimate risk

Drug Development - U.S. FDA grants orphan drug status to monoclonal antibody for treating type 1 diabetes

Endocrinology - Adiponectin levels are more closely linked to current body size than birthweight

Endocrinology - Insulin resistance in the Zucker diabetic fatty rat was characterized

Endocrinology - Metabolic control may be improved by targeting the BA-TGR5-cAMP-D2 signaling pathway

Endocrinology - No link between serum TSH or free T4 and BMI in euthyroid subjects found

Endocrinology - Researchers detail new studies and findings in the area of endocrinology

Epidemiology - Children in the Deep South face higher health risks than other U.S. children

Epidemiology - Latino field laborers not eating what they grow

Finance - Sangamo reports consolidated net loss of $2.7 million for 2005 fourth quarter

Fitness & Wellness - Overweight and related health problems best solved by cutting back on calories

Fitness & Wellness - Value of exercise training and antioxidants in diabetes treatment highlighted

Genetics & Genomics - AQP7 is differentially expressed in adipose tissue of lean and obese high fat consumers

Genetics & Genomics - Metabolic syndrome prevalence in aboriginal Canadians finds three candidate genes

Genetics & Genomics - Urinary albumin excretion may be controlled by genes on chromosomes 22q, 5q and 7q

Home Healthcare - Study shows patient self-monitoring market is positioned for growth

Hyperglycemia & Hepatitis C - Hyperglycemia in those with hepatitis C displays an unconventional diabetic phenotype

Hypertension - Hypertension can be predicted by metabolic variations, lipid profiles, and blood pressure

Hypertension - New data illuminates research in hypertension

Inflammation - Systemic inflammation and adiposity are strongly associated in women

Information Technology - Glucon selects NetRegulus' enterprise compliance software to manage clinical trial schedule

Kidney Transplantation - Post-transplant diabetes mellitus is associated with high tacrolimus concentration-dose ratios

Metabolic Syndrome - Cardiovascular risk may be increased by insulin resistance in metabolic syndrome

Metabolic Syndrome - New metabolic syndrome definition increases apparent prevalence in U.S. adults

Neuroscience - Food cravings may be caused by sensitization of the mesolimbic dopamine system

Obesity - Results of RIO-North America obesity study with rimonabant published in JAMA

Obesity - siRNA-based strategy validating novel drug targets in obesity and diabetes presented

Obesity Complications - Obese adolescents experience a higher incidence of gallbladder stone disease

Obesity Complications - Obese children experience adipocyte fragility which can instigate 'inflammatory' process

Obesity Complications - Obese renal transplant patients experience increased risk of DGF and low graft survival

Obesity Complications - Obesity is linked to higher death rates from cardiovascular diseases, diabetes, and accidents

Obesity Complications - Obesity is related to pulmonary problems in children

Obesity Complications - Obesity requires special perioperative management including arterial monitoring

Obesity Complications - tHcy levels are not link to carotid IMT in obese during the nonatherogenic stage

Obesity Epidemiology - Lower levels wealth and perception of wealth increase odds of being physically inactive

Obesity Epidemiology - Obesity and weight gain is common following renal transplantation

Obesity Pathogenesis - Body mass index, waist circumference contribute to increases in insulin resistance in nondiabetics

Obesity Pathogenesis - Cardiac myocyte apoptosis is linked to higher DNA damage and mortality in obesity model

Obesity Pathogenesis - Hedgehog signaling plays a conserved role in inhibiting fat formation

Obesity Pathogenesis - Impairment of adipose tissue development by hypoxia is not mediated by PAI-I

Obesity Pathogenesis - MC3/4-R metabolic and cardiovascular actions are preserved in diet-induced obesity

Obesity Pathogenesis - Novel loci affecting TG, HDL, and fat mass were identified in MRL/MpJ x SJL/J inbred mice

Obesity Pathogenesis - Obesity related gene Tgl4 is functional ortholog of mammalian adipose triglyceride lipase

Obesity Pathogenesis - Pentose pathway flux regulates 11 beta-HSD1

Obesity Pathogenesis - Researchers' data advance obesity pathogenesis research

Obesity Pathogenesis - Researchers' work adds to obesity pathogenesis body of knowledge

Obesity Pathogenesis - Studies add new findings to obesity pathogenesis body of knowledge

Obesity Therapy - Antiobesity agent tungstate targets metabolism and signal processes in adipose tissue

Obesity Therapy - New findings in the area of obesity therapy described

Obesity Therapy - Obese treated by RYGBP experience higher morbidity and mortality risk after extraluminal leaks

Obesity Therapy - Orlistat increased nitric oxide synthase levels in the small intestinal mucosa

Obesity Therapy - Rimonabant shows modest benefit in reducing weight, improving HDL levels

Obesity/Prostate Cancer Associations - Obesity may hinder detection of prostate cancer

Obesity/Sleep Apnea Associations - High sleep apnea incidence found in morbidly obese patients with tibia vara

Ophthalmology - Eyes with diabetic retinopathy may benefit from ephrinA1 therapy

Pediatric Obesity Comorbidity - Significant numbers of obese children have associated comorbidities

Pediatric Obesity Risk Factors - Visceral adiposity is a risk factor for pediatric nonalcoholic fatty liver disease

Pediatrics Type 1 Diabetes - IDAEPs may indicate low brain serotonergic neurotransmission in type 1 diabetes patients

Personnel - Charles T. Liamos joins board of directors of OmniPod Insulin Management System maker

Personnel - Renee C. LeBoeuf, PhD, diabetes researcher, joins stem-cell company's advisory board

Pneumococcal Pneumonia - Leptin corrects host defense defects after acute starvation in pneumococcal pneumonia

Proteomics - Findings in proteomics provide new insights

Proteomics - TC-PTP and PTP1B role in signal transduction and diabetes, obesity, and cancer is reviewed

Statins - Research in statins provides new insights

Telemedicine - Glycemic control, blood pressure, and LDL levels are improved by telemedicine

Type 1 Diabetes - Diabetes mellitus show upregulation of CCL3 and CCL4 and downregulation of CCL2

Type 1 Diabetes - Juvenile diabetes foundation partners with Stemnion on adult stem cell project

Type 1 Diabetes - Type 1 diabetes cure may be found in islet transplants

Type 2 Diabetes - Diastolic dysfunction is linked to anemia in patients with type 2 diabetes

Type 2 Diabetes - Glycemic response to metformin and sulphonylureas in nonobese and obese is similar

Type 2 Diabetes - Metabasis' MB07803 for the treatment of diabetes enters clinical trail

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