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Phase II clinical trial in neuropathic pain begins

Published in Obesity and Diabetes Week, March 13th, 2006

DOV Pharmaceutical, Inc., (DOVP) announced that it has initiated dosing in a phase II clinical trial of bicifadine, an analgesic, in patients with painful diabetic peripheral neuropathy.

This is the first study of bicifadine in patients with neuropathic pain. The trial is a randomized, multiple-dose, open-label, 2-phase overlap trial designed to assess the efficacy and safety of bicifadine and potential interactions of bicifadine and oxycodone used concurrently. DOV expects to complete dosing in the third quarter of this year.

The clinical trial will randomize 50 patients with painful diabetic neuropathy into 2 parallel 4-week treatment groups. In...

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