Diabetes Pathogenesis
GNB3 825C >T polymorphism do not seem to be involved in metabolic syndrome
Published in Obesity and Diabetes Week, March 20th, 2006
"The 825C >T polymorphism in the gene encoding the G protein beta 3 subunit (GNB3) causes enhanced G protein activation and increased in vitro cell proliferation. This polymorphism is also repeatedly associated with an increased risk of hypertension and has been studied in relation to obesity with divergent results. Only a few association studies have investigated whether this polymorphism is related to type 2 diabetes or the metabolic syndrome," scientists in Denmark report.
G. Andersen and colleagues at the Steno Diabetes Center proposed to "estimated the impact...
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