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Obesity and Diabetes Week

Susan Hasty, Publisher

Table of Contents . . . March 27th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Obesity and Diabetes Week | Other Publications

Complementary & Alternative Medicine - Diacylglycerol oil supplements may be able to manage obesity in type 2 diabetics

Diet & Nutrition - Polyunsaturated fatty acids induce adiponectin and show antidiabetic properties

Insulin Sensitivity - IL-1 receptor antagonist upregulated in diet-induced obesity rodent model

Obesity Pathogenesis - Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific Pomc-/- mice

Obesity Pathogenesis - High adiponectin levels seen in Prader-Willi syndrome as compared with other obesity types

Adverse Drug Reaction - 13-cis-retinoic acid-induced reduction in insulin sensitivity raises fasting adiponectin levels

Adverse Drug Reaction - Antipsychotic medication does not necessarily induce diabetes

Adverse Drug Reaction - Fulminant type 1 diabetes caused by DHS with HHV-6 infection is reviewed

Angiology - High-dose folic acid does not protect vascular endothelium from IR injury in humans

Angiology - Metabolic syndrome amplifies the LDL-C associated increases in carotid atherosclerosis

Angiology - Visceral fat obesity contributes to thoracic aorta tortuosity in poststroke patients

Atherosclerosis - Hyperglycemia plus inflammation is linked to early carotid atherosclerosis progression

Behavioral Medicine - Weight reduction strategies needed for obese with intellectual disability

Carcinogenesis - Hyperinsulinism plus hyperglycemia induces hepatocellular carcinomas development

Cardiology - Findings in cardiology provide new insights

Cardiovascular Disease - Cardiovascular and metabolic effects of natriuretic peptides reviewed

Childhood Diabetes - Diabetes risk could be influenced by programs to change overfeeding, sedentary lifestyle

Chronic Conditions - Study shows Ohioans needlessly suffer because they are not properly caring for chronic conditions

Complementary & Alternative Medicine - Diabetic cardiomyopathy prevention by zinc supplement is mediated by cardiac MT levels

Complementary & Alternative Medicine - Ecdysterone exerts an insulin independent glucose-lowering effect in hepatocytes

DNA Research - Tetrahydrobiopterin supplementation improves vascular dysfunction in insulin-resistance

Diabetes Care - DAWN Study finds improvements needed in chronic-care model for diabetes therapy

Diabetes Complications - Aortic depressor nerves show signs of axonal atrophy in chronic diabetes

Diabetes Complications - Corneal hydration control in contact lens wearers altered in diabetics

Diabetes Complications - Diabetes related bone loss is linked to disordered osteoclast formation in RAGE-deficient mouse

Diabetes Complications - Diabetes-related limb ischemia resolves in models treated with benfotiamine

Diabetes Complications - Diabetics have higher stroke, graft patency, and lib salvage complication risk postsurgery

Diabetes Complications - Elevated plasma PLTP activity predicts carotid intima-media thickness in type 2 diabetes

Diabetes Complications - Higher rate of dental caries among children with type 1 diabetes mellitus

Diabetes Complications - Hypertension and diabetic complications independent of ethnic origin

Diabetes Complications - Pioglitazone reduces proinflammatory markers in diabetic nephropathy patients

Diabetes Complications - Renal lesions of chronic nephropathies and diabetes reviewed

Diabetes Complications - Researchers' data advance diabetes complications research

Diabetes Control - Apidra now available in the U.S. for hyperglycemia

Diabetes Control - Blood glucose self-monitoring linked to lower morbidity and mortality in diabetes

Diabetes Drug Therapy - Glimepiride and rosiglitazone improve metabolic control in conjunction with metformin

Diabetes Pathogenesis - Basal phosphorylation of DSM myosin mediated by upregulation of Rho-kinase beta and CPI-17

Diabetes Pathogenesis - EtOH exposure in womb raised gluconeogenesis and impaired hepatic gluconeogenic gene response

Diabetes Pathogenesis - Eukaryotic elongation factor 1A-1 plays a roll in lipotoxic cell death

Diabetes Pathogenesis - Glucose toxicity may contribute to microalbuminuria

Diabetes Pathogenesis - Heterodimeric nuclear receptors useful in diabetes pathophysiology and therapy

Diabetes Pathogenesis - High glucose stimulates GEC hypertrophy through ROS-dependent activation in diabetics

Diabetes Pathogenesis - Insulin resistance in type 2 diabetes is reviewed

Diabetes Pathogenesis - Insulin secretion directly regulated by angiotensin II in human islets of Langerhans

Diabetes Pathogenesis - Recent findings illuminate research in diabetes pathogenesis

Diabetes Pathogenesis - Studies describe new findings in diabetes pathogenesis research

Diabetes Research - Diabetics with uncontrolled blood pressure identified using administrative databases

Diabetes Research - Vascular relaxation improved by chronically elevated CO levels

Diabetes Therapy - 1-hydroxy-4,5,6-substituted 2(1H)-pyrimidinones complexes improve glucose tolerance

Diabetes Therapy - Antidiabetic and hypolipidemic effects of Collybia confluens mycelia observed in diabetic rat

Diabetes Therapy - Antidiabetic effects observed for alkaline-reduced water in OLETF rats

Diabetes Therapy - Diabetes and intestinal disease therapy may make use of proglucagon-derived peptides

Diabetes Therapy - Glenmark's anti-diabetic DPP-IV inhibitor successfully completes Phase I in U.K.

Diabetes Therapy - Metformin therapy improved AMPK and aPKC activity in muscles of diabetics

Diabetes Therapy - NN344 may be a longer lasting and more predictable insulin supplement

Diabetes Therapy - Once-daily gliclazide-modified release improved blood glucose control in type 2 diabetics

Diabetes Therapy - Premixed insulin analogues for the treatment of diabetes mellitus are reviewed

Diabetes Therapy - Research add new data to diabetes therapy body of knowledge

Diabetes Therapy - Researchers' data advance diabetes therapy research

Diabetes Therapy - Studies add new findings to diabetes therapy body of knowledge

Diabetes Therapy - Sulfonylureas, biguanides and insulin overdoses lead to heath risk and occasionally death

Diabetic Neuropathy - Hyperglycemia-induced diabetic neuropathy reversed by GDNF activation of PI3K/Akt pathway

Diagnostics - Morbid obesity with SBO after gastric bypass are best treated by laparoscopic surgery

Diet & Nutrition - Body fat does not influence 25(OH)D elevation following vitamin D supplement

Diet & Nutrition - Body fat reduced by protein hydrolysate in genetically obese rats

Diet & Nutrition - Findings advance knowledge in diet & nutrition research

Diet & Nutrition - High-carbohydrate and high-protein diets appear as healthy options for insulin-resistant

Diet & Nutrition - PPAR-gamma response element activity and cardiovascular morbidity affected by fatty acids

Diet & Nutrition - Researchers' data advance diet & nutrition research

Diet & Nutrition - Researchers' work adds to diet & nutrition body of knowledge

Diet & Nutrition - Two-thirds of U.S. adults consider themselves to be healthy eaters, Harris survey shows

Diet & Nutrition - Weight gain inversely associated with consumption of dairy products

Diet & Nutrition - Weight loss observed in rats fed powdered scallop shells

Drug Safety - Inhaled insulin absorbed best as dry powder either with or without alkylglycosides

Endocrinology - Cannabinoid receptors regulate Ca2+ signals and insulin secretion in pancreatic beta-cell

Endocrinology - Hepatic glycogen cycling measurement method was developed

Endocrinology - Researchers detail new studies and findings in the area of endocrinology

Finance - DexCom reports Q4 net loss of $12.1M, 2005 net loss of $30.8M

Finance - EndoGastric Solutions completes $32 million series C financing

Finance - Obesity management company reports private placement of common stock and warrants

Finance - WellGen's $3 million financing complete; funds earmarked for obesity, inflammatory programs

Fitness & Wellness - Americans are keeping New Year's resolutions to exercise

Fitness & Wellness - Body fat is regulated in part by overall energy expended during alert periods

Genetics & Genomics - Body fat and blood pressure gene search in African-American adult twins is inconclusive

Genetics & Genomics - Low CD36 expression in PWS indicate abnormal lipid and glucose homeostasis control

Genetics & Genomics - SOCS3 polymorphisms not associated with body weight, insulin sensitivity or lipid profile

Genetics & Genomics - Studies describe new findings in genetics & genomics research

Geriatrics - APO A-V-1131T->C polymorphism frequency linked to morbidity in elderly population

HIV/AIDS Complications - HIV-infected women may experience increased intramyocellular lipid levels

Healthcare Costs - Obesity health care may be more costly due to high life expectancy rate among obese

Hypertension - Hypertension is not associated with leptin in Japanese-Brazilian women

Laparoscopic Adjustable Gastric Banding - LABG has lowest complication rate when comparing laparoscopic bariatric procedures

Market Analysis - Driven by sanofi-aventis, Pfizer blockbusters, metabolic syndrome market to nearly double

Medical Devices - Axis-Shield gets CLIA waiver for Afinion point-of-care system with diabetes monitoring test

Medical Devices - BD Medical notifying users of potential malfunction in blood glucose meter

Mergers & Acquisitions - Pfizer completes acquisition of Exubera worldwide rights from sanofi-aventis

Molecular Biology - Vascular elastin calcification is subject to osteogenic and degenerative control

Morbid Obesity - Morbid obesity does not adversely affect laparoscopic Nissen fundoplication outcome

Obesity & Asthma - Obesity may influence response to asthma medications

Obesity Complications - Extreme obesity strongly associated with attempted suicide

Obesity Complications - Obese need to be monitored for neurologic complications after surgery

Obesity Complications - Obesity does not significantly influence accuracy of blood pressure measurements

Obesity Diagnostics - Adiposity rebound estimates made by visual approach reflect physiological basis of rebound

Obesity Diagnostics - Obesity among children can be estimated by parent reported weight and height measurements

Obesity Epidemiology - New findings in obesity epidemiology described

Obesity Epidemiology - Obesity linked to promoter polymorphism in macrophage migration inhibitory factor gene

Obesity Pathogenesis - Low blood volume and high peripheral adrenergic constriction shown in obese rat model

Obesity Pathogenesis - New data illuminates research in obesity pathogenesis

Obesity Pathogenesis - New findings in the area of obesity pathogenesis described

Obesity Pathogenesis - New research in the area of obesity pathogenesis detailed

Obesity Pathogenesis - Obese and elderly MA levels linked to insulin sensitivity and protein turnover rates

Obesity Pathogenesis - Reports add new data to obesity pathogenesis research

Obesity Pathogenesis - Resistin, insulin resistance index, and weight status in obese youth are not related

Obesity Pathogenesis - TNF-alpha autoregulates its own biosynthesis resulting in elevated TNF-alpha levels in obese

Obesity Research - Obesity studies need to acclimatize rats to experimental conditions

Obesity Therapy - Initially LGBP groups lose more weight than LASGB, both show similar comorbidity improvements

Obesity Therapy - Obese women undergoing diet and exercise training have improved neurovascular control

Obesity Therapy - Obesity intervention was developed for people with spinal cord injury

Obesity Therapy - Octreotide LAR resulted in weight loss in obese adults with insulin hypersecretion

Obesity Therapy - Positive 2-year trial results of rimonabant treatment in overweight patients published

Obesity Therapy - Reports advance knowledge in obesity therapy research

Obesity Therapy - Sibutramine therapy should be continued for 3 months before predicting results

Obesity Therapy - Studies add new findings to obesity therapy body of knowledge

Obesity Therapy - Studies advance knowledge in obesity therapy research

Osteoporosis - Osteoporosis and obesity link may be due to fat infiltration of bone marrow

Proteomics - PGC-alpha expression and triacylglycerol levels were found to be inversely related in muscle

Pulmonary Tuberculosis & Diabetes - Pulmonary tuberculosis treatment outcome not altered by diabetes

Quality of Life - Diabetics do not have a diminished quality of life

Quality of Life - Health-related quality of life among obese youth appears to be lower than peers

Type 2 Diabetes - In diabetes, altered control of cutaneous vasodilation may lead to impaired thermoregulation

Type 2 Diabetes - Metformin is not linked to higher lactic acidosis risk in type 2 diabetics

Type 2 Diabetes - New type 2 diabetes candidate marker for progression of microvascular disease discovered

Type 2 Diabetes - Phase I/II study of PC-DAC:Exendin-4 for type 2 diabetes to be initiated by ConjuChem

Type 2 Diabetes - Sister chromatid exchanges experienced more frequently in type 2 diabetics

Type 2 Diabetes - Supplemental NDA submitted seeking to use exenatide injection with TZDs in type 2 diabetes

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