Diabetes Complications
Diabetes-related limb ischemia resolves in models treated with benfotiamine
Published in Obesity and Diabetes Week, March 27th, 2006
According to recent research published in the journal Diabetologia, "Benfotiamine, a vitamin B1 analogue, reportedly prevents diabetic microangiopathy. The aim of this study was to evaluate whether benfotiamine is of benefit in reparative neovascularization using a type I diabetes model of hindlimb ischemia."
"We also investigated the involvement of protein kinase B (PKB)/Akt in the therapeutic effects of benfotiamine. Streptozotocin-induced diabetic mice, given oral benfotiamine or vehicle, were subjected to unilateral limb ischemia. Reparative neovascularization was...
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