Published in Obesity and Diabetes Week, April 3rd, 2006
According to recent research from England, "Heterozygous mutations in the transcription factors hepatocyte nuclear factor (HNF)-1 alpha and -1 beta result in MODY (maturity-onset diabetes of the young). Despite structural similarity between HNF-1 alpha and -1 beta, HNF-1 beta mutation carriers have hyperinsulinemia, whereas HNF-1 alpha mutation carriers have normal or reduced insulin concentrations."
A. Brackenridge and colleagues at the University of Surrey assessed "whether HNF-1 beta mutation...
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